Pediatrics & Neonatology

2021-10-10 12:21:14 SSO therapy universally for all newborn infants is not effective in reducing NMR.

#skin
https://doi.org/10.1371/journal.pmed.1003680 Open / Comment

2021-10-10 12:16:38 The study indicated that preterm DM does not affect the growth of very-low-birth weight infants. Further, it significantly reduces feeding intolerance, helps achieve full enteral feeding early, and has protective effects against necrotizing enterocolitis and sepsis. Thus, compared with #formula, preterm DM can lower the rate of infection in preterm infants and is worthy of promotion.

#milk
http://dx.doi.org/10.29219/fnr.v65.5346 Open / Comment

2021-10-10 12:14:47 Experimental results underscore that increasing the signal quality leads to a reduction in vital sign error, with only high-quality recordings having mean absolute error of less than 5 beats per minute, as required for clinical usage. Open / Comment

2021-10-10 12:13:00 Overall, WM microstructural maturity measured through DTI metrics was reduced in preterm infants receiving the standard-of-care in comparison to full-term newborns, whereas preterm infants exposed to the #music intervention demonstrated significantly improved white matter maturation in acoustic radiations, external capsule/ claustrum/extreme capsule and uncinate fasciculus, as well as larger amygdala volumes, in comparison to preterm infants with standard-of-care.

#development
https://doi.org/10.1016/j.neuroimage.2019.116391 Open / Comment

2021-10-10 12:11:03 Among 5.5-year-old very preterm born children, subgroups can be distinguished with distinct outcome profiles that vary in severity, type, and combinations of deficits. This information is important for the #development of interventions that are tailored to the needs of large subgroups of children across multiple domains of functioning. Open / Comment

2021-10-10 12:09:12 Despite decades of research, our findings indicate that the CoE is low to very low for most of the commonly attributed risk factors of #PVL.

https://doi.org/10.1016/j.pediatrneurol.2021.08.003 Open / Comment

2021-10-10 12:07:33 There are several areas of uncertainty in practice, including the optimal and relative intakes of macronutrients and the optimal timing of initiation of parenteral #nutrition after birth. High quality randomised controlled trials powered to detect differences in long term functional outcomes are needed to determine best practice in preterm parenteral nutrition practice.

https://doi.org/10.1016/j.earlhumdev.2021.105468 Open / Comment

2021-09-09 11:40:40 The efficacy of single probiotic supplements is limited, compared with combined use of probiotics. Bifidobacterium plus prebiotic supplementation is the optimal intervention in reducing mortality; Lactobacillus plus prebiotic supplementation is the optimal intervention in reducing NEC morbidity. To achieve optimal effect on premature infant health, combined use of prebiotic and probiotic, especially Lactobacillus or Bifidobacterium, is recommended.

#probiotics
https://doi.org/10.1542/peds.2020-0706 Open / Comment

2021-09-09 11:31:52 The overall incidence of low blood #pressure is less than previously determined with less than one quarter of infants having at least one numerically low BP in the first days of life. The mean time to presentation with low BP is early, less than 6 hours.
Conducting studies of cardiovascular instability in extreme preterm infants is challenging, and alternative trial designs and consent strategies need to be considered.

#hypotension
http://dx.doi.org/10.1136/archdischild-2020-320241 Open / Comment

2021-09-09 11:29:48 Many methods for #temperature monitoring in neonates are currently available, each with their own advantages and disadvantages. However, the accuracies of different devices are hard to determine due to variable methodologies used in relevant studies and hence, further research that addresses these gaps is needed.

https://doi.org/10.3389/fped.2021.732810 Open / Comment