Answer B (correct answer): The Michaelis constant, Km, represe | Usmle materials 2020

Answer B (correct answer): The Michaelis constant, Km, represents how avidly an enzyme binds to substrate. The lower the Km value, the more easily
the enzyme binds substrate. Systems with a low Km rapidly reach Vrnax because the enzyme is highly effective at binding substrate. Conversely,
enzymes with a high Km require large amounts of substrate to reach Vmax. ALDHC has a much lower Km compared to ALDHJ. Thus, ALDHC binds to
substrate with higher affinity.