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Your gut bacteria make LPS, or lipopolysaccharides, when they | Dave Asprey Official

Your gut bacteria make LPS, or lipopolysaccharides, when they aren’t happy. This can happen when you eat only protein and fat and deprive them of fiber.

Lipopolysaccharides enter the bloodstream and cause various symptoms, including fatigue, anxiety, depression, poor sleep, and dysregulated blood glucose levels. They also may increase your risk of getting heart disease and metabolic syndrome.

For your gut bacteria to be happy, you want to feed and nourish them with compounds found in plant foods. That’s why I recommend cyclical ketosis instead of shunning all carbs indefinitely.

Studies show that prebiotic fiber, such as the kind found in asparagus and radishes, and polyphenols, such as the ones found in dark veggies and coffee, help feed your gut bacteria and can lead to lower LPS levels.