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What are allotransplantation and xenotransplantation? Allo | Ask Me

What are allotransplantation and xenotransplantation?

Allotransplantation
(“allo” means "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. The transplant is called an allograft, allogenic transplant, or homograft, so all human tissues and organs when transplanted from one person to another are scientifically called allografts.

Allotransplantation is different to xenotransplantation (“xenos” is the Greek root meaning "foreign"), or heterologous transplant, which is the transplantation of living cells, tissues or organs, called xenografts or xenotransplants, from one species to another. For example, pigs’ heart valves transplanted into a human is a xenotranplantation.

Xenotransplantation, when human cells are implanted into animals , is a research technique frequently used by scientists in pre-clinical studies , for instance in oncology.

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