Causes of subtotal villous atrophy Subtotal villous atrophy is a histopathological term used to describe blunting of intestinal villi (villi becomes short) with hyperplasia of the crypts.
This results in a reduced surface area for absorption and therefore the patient may present with diarrhea and malabsorption, causes include :
1) Coeliac disease.
2) Tropical sprue.
3) Giardia Lamblia infection.
4) Microscopic colitis.
5) Dermatitis herpetiformis.
6) HIV-related enteropathy.
7) Radiation enteritis.
8) Hypogammaglobulinemia.
9) Small intestinal lymphoma.
10) Zollinger Ellison syndrome.
Above fig shows subtotal villous atrophy in coeliac disease.
