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Class I mutations of familial hypercholesterolemia includes | International surgical boards

Class I mutations of familial hypercholesterolemia includes
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32%
Failure to synthesize LDL receptors
23%
Failure of transport of LDL receptors across Golgi apparatus
22%
Failure to LDL receptor to internalize LDL following binding
23%
Failure of LDL receptor-LDL complex to dissociate following endocytosis
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