Note The acidotic state caused by Inadequate tissue perfusion | International surgical boards
Note
The acidotic state caused by Inadequate tissue perfusion in the shocked patient was found experimentally to be a some what desirable state, as acidosis helps oxygen offloading from hemoglobin providing better oxygen delivary, also in ex vivo experiments cells were found to better tolarate acidosis than alkalosis, with that being said, sodium bicarbonate therapy in shocked patients to offset acidosis is not effective, as it can worsen intracellular acidosis by increased Co2 diffusion into the cells which is produced by the buffering process.
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