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The latest Messages 7
2021-03-28 10:01:17
Genomics and Human Genome project:
(1) The term genome has been introduced by Winkler in 1920 and the genomics is relatively new, coined by Thomas Rodericks in 1986.
(2) Genomics is the subdiscipline of genetics devoted to the mapping, sequencing and functional analysis of genomes. Genomics is subdivided into following types:
(a) Structural genomics: It is the study of genome structure deals with the complete nucleotide sequences of the organisms.
(b) Functional genomics: It is the study of genome function which includes transcriptome and proteome. Transcriptome is a complete set of RNAs transcribed from a genome while proteome is a complete set of proteins encoded by a genome and aims the determination of the structure and function of all the proteins in living organisms.
(3) The human genome project, sometimes called “biology’s moon shot”, was launched on october 1, 1990 for sequencing the entire human genome of 2.75 billion (2.75 ´ 109 or 2750000 bp or 2750000 kilobase pairs or 2750 megabase pairs) nucleotide pairs.
(4) Two important scientist associated with human genome are Francis Collins, director of the Human Genome Project and J. Craig Venter, founding president of Celera genomics.
(5) The complete sequencing of the first human chromosome, small chromosome 22, was published in December 1999.
Prospects and implications of human genome:
(1) The genome project is being compared to the discovery of antibiotics.
(2) Efforts are in progress to determine genes that will revert cancerous cells to normal.
(3) The human genome sequencing not only holds promise for a healthier living. It also holds the prospects of vast database of knowledge about designer drugs, genetically modified diets and finally our genetic identity.
@NEET_NIKALO1
FAILA DO ISE HAR JAGAH
10.1K viewsedited 07:01
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