Patients with nephrotic syndrome are at an increased risk of v | FreeMedSite

Patients with nephrotic syndrome are at an increased risk of venous thromboembolism.

Mechanism:
1. Reduced antithrombin III due to glomerular dysfunction
2. Platelet hyperactivity
3. Renal loss of plasmin impairing fibrinolysis.

Nephrotic Triad
1. oedema
2. proteinuria and
3. hypoalbuminemia.