Functions Of Antibody : IgG – Protects body fluids. IgA – Protects body surfaces. IgM – Protects body blood stream. IgE – Mediates regional hypersensitivity. IgD – Activation of B-lymphocyte Trick - GAMDE (गम दे) First line of defence : Skin, Mucous membrane Second line of defence : Neutrophils, Monocytes, Macrophage, interfero Third line of defence : Specific immunity by T- and B-lymphocytes 288 viewsedited 07:21