Cardiology

2021-08-30 17:14:54 #ESCCongress – RCT: Among asymptomatic patients with severe carotid stenosis, carotid surgery and stenting carry similar risks, and the long-term risk of stroke was comparable. There was no medically treated arm in this study.

https://www.linksmedicus.com/news/esccongress-rct-among-asymptomatic-patients-severe-carotid-stenosis-carotid-surgery-stenting-carry-similar-risks-long-term-risk-stroke-comparable-no-medically/ Open / Comment

2021-08-30 17:09:48 #ESCCongress – RCT: Small benefit from systematic screening for atrial fibrillation in older adults – After a median follow-up of 6.9 y there were fewer events (stroke, embolism, bleeding, and death) in the intervention group (31·9%) vs. control group (33·0%).

https://www.linksmedicus.com/news/esccongress-rct-small-benefit-systematic-screening-atrial-fibrillation-older-adults-median-follow-6-9-y-fewer-events-stroke-embolism-bleeding-death/ Open / Comment

2021-08-30 17:04:57 #ESCCongress – RCT: Initial hypertension treatment with a single pill with 4 drugs at quarter doses (irbesartan 37.5 mg, amlodipine 1.25 mg, indapamide 0.625 mg, and bisoprolol 2.5 mg) achieved better BP lowering vs. standard monotherapy (irbesartan 150 mg).

https://www.linksmedicus.com/news/esccongress-rct-initial-hypertension-treatment-single-pill-4-drugs-quarter-doses-irbesartan-37-5-mg-amlodipine-1-25-mg-indapamide-0-625-mg-bisoprolol-2-5-mg-achieved-better/ Open / Comment

2021-08-30 16:59:58 #ESCCongress – RCT: Immediate coronary angiography after out-of-hospital cardiac arrest without ST-segment elevation did not improve outcomes compared to delayed/selective angiography.

https://www.linksmedicus.com/news/esccongress-rct-immediate-coronary-angiography-hospital-cardiac-arrest-without-st-segment-elevation-not-improve-outcomes-compared-delayed-selective-angiography/ Open / Comment

2021-08-30 16:55:23 #ESCCongress – RCT: Finerenone reduced CV events in patients with kidney disease and type 2 diabetes (12.4% vs. 14.2% during a median follow-up of 3.4 years), but the risk of hyperkalemia was increased (10.8% vs. 5.3%).

https://www.linksmedicus.com/news/esccongress-rct-finerenone-reduced-cv-events-patients-kidney-disease-type-2-diabetes-12-4-vs-14-2-median-follow-3-4-years-risk-hyperkalemia-increased/ Open / Comment

2021-08-30 16:48:24 #ESCCongress – RCT: In patients who underwent PCI at high bleeding risk, 1 month of dual antiplatelet therapy was noninferior to the continuation of dual therapy for at least 2 additional months and resulted in a lower incidence of bleeding events.

https://www.linksmedicus.com/news/esccongress-rct-patients-underwent-pci-high-bleeding-risk-1-month-dual-antiplatelet-therapy-noninferior-continuation-dual-therapy-least-2-additional-months-r/ Open / Comment

2021-08-30 16:43:21 #ESCCongress – RCT: In patients with A. Fibrillation who underwent TAVR, Edoxaban was noninferior to Vit. K Antagonist regarding the composite primary outcome of adverse clinical events, but resulted in a higher incidence of major bleeding.

https://www.linksmedicus.com/news/esccongress-rct-patients-fibrillation-underwent-tavr-edoxaban-noninferior-vit-k-antagonist-regarding-composite-primary-outcome-adverse-clinical-events-resulted/ Open / Comment

2021-08-30 16:38:06 #ESCCongress – RCT: SGLT2 inhibition reduced the combined risk of cardiovascular death or hospitalization in patients with heart failure and a preserved ejection fraction, regardless of the presence or absence of diabetes.

https://www.linksmedicus.com/news/esccongress-rct-sglt2-inhibition-reduced-combined-risk-cardiovascular-death-hospitalization-patients-heart-failure-preserved-ejection-fraction-regardless-presence-o/ Open / Comment