The locus coeruleus, which in Latin means 'blue spot', is the | NeuroPsychiatry

The locus coeruleus, which in Latin means "blue spot", is the principal site for brain synthesis of norepinephrine (noradrenalie).
The locus coeruleus and the areas of the body affected by the norepinephrine it produces are described collectively as the locus coeruleus-noradrenergic system or LC-NA system.

Norepinephrine may also be released directly into the blood from the adrenal medulla.