NIIMA, Network of Immunity in Infection, Malignancy and Autoimmunity

2022-09-01 16:13:24 Less than 12 hours left...

Submit your abstracts: https://docs.google.com/forms/d/e/1FAIpQLSeCryI75wR5SAkcLsB1Ent_1GyvHzkM4TJE_TihQB0w63OCyQ/viewform?usp=sf_link

Submission deadline: September 1st

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2022-08-30 16:30:29 Efficacy of tocilizumab in the treatment of COVID-19: An umbrella review

New Paper by USERN Interest Group

The aim of this umbrella review was to determine the efficacy of tocilizumab in treating COVID-19, and to provide an overview of all systematic reviews on this topic. 

Tocilizumab treatment reduced the risk of intubation, mortality and the length of hospital stay, without increasing the risk of superimposed infections in COVID-19 patients. Therefore, tocilizumab can be considered an effective therapeutic agent for treating patients with COVID-19.

Source: https://doi.org/10.1002/rmv.2388

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2022-08-29 20:56:17 The 7th International USERN Congress and Prize Awarding Festival

To register:
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2022-08-29 11:20:08 Aging, testosterone, and neuroplasticity: friend or foe?

New Paper by USERN Interest Group

In the present review, we discuss the influence of environmental factors, aging, and gender on testosterone-associated alterations in neuroplasticity, as well as the two-sided actions of testosterone in the nervous system. Finally, we provide practical insights for further study of pharmacological treatments for hormonal disorders focusing on restoring neuroplasticity.

Source: https://doi.org/10.1515/revneuro-2022-0033

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2022-08-28 05:01:02 Invitation to vote for the “USERN Prize 2022 Candidates”

For the seventh year, the USERN is proud to announce USERN Prize Nominees in five main branches of science from a total of 300 candidates.

From the top-10 selected candidates in each field of science, one applicant will be announced as the Winner of the USERN Prize 2022 after the 2nd round of voting by the top 1% scientists and the Nobel Laureates.

And now, your votes will be accounted to nominate 5 applicants in each field.

Deadline for abstract submission and voting for the "USERN Prize 2022": September 1st, 2022

Vote to choose your best young scientist in 2022!

Congress registration

More information about the USERN prize

Please feel free to share this post with your colleagues, to help the USERN Prize Organizing Team to select the top 5 for the USERN Prize 2022.

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2022-08-27 12:16:23 The 8th International Festival of Paintings for Pediatric Patients

Vote to select the best paintings via:
https://docs.google.com/forms/d/e/1FAIpQLSdUNr6WK9lZ9dWhHAytIUkBl2cgAJz_Nv0q79jFeS_QmkvPXg/viewform

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2022-08-25 16:30:12 Novel DNMT3B Mutation in a Patient with Immunodeficiency, Centromeric Instability, and Facial Anomalies (ICF) Syndrome and a Bronchopulmonary Collateral Artery

New Paper by USERN Interest Group

This article describes a novel homozygous DNMT3B mutation in an Iranian boy with ICF1. It is associated with recurrent infections, hypogammaglobinemia, neutropenia, mild facial anomalies, and a bronchopulmonary collateral artery.

Source: https://doi.org/10.2174/1871530322666220822141722

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2022-08-24 16:28:23 Hesperetin as an anti-SARS-CoV-2 agent can inhibit COVID-19-associated cancer progression by suppressing intracellular signaling pathways

New Paper by USERN Interest Group

Hesperetin, an aglycone metabolite of hesperidin with high bioavailability, recently gained attention due to its anti-COVID-19 and anti-cancer properties.

This study proposes that hesperetin not only can be used as an anti-COVID-19 agent but also can reduce the risk of multiple cancer progression by suppressing several intracellular signaling pathways in cancer patients with COVID-19.

In this review, we attempted to provide evidence demonstrating anti-COVID-19/cancer properties of hesperetin with several mechanisms.

Source: https://doi.org/10.1007/s10787-022-01054-3

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2022-08-22 20:20:24 Unique opportunity to present your scientific activities in an international network

Submit your abstracts: https://docs.google.com/forms/d/e/1FAIpQLSeCryI75wR5SAkcLsB1Ent_1GyvHzkM4TJE_TihQB0w63OCyQ/viewform?usp=sf_link

Submission deadline: September 1st

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2022-08-20 05:31:02 Elevated neopterin in tuberculosis and co-infection with HIV and the effect of treatment: A systematic review, meta-analysis, and meta-regression

New Paper by USERN Interest Group

Meta-analysis showed higher blood NEO levels in patients with active TB than healthy controls, with a large effect size of 1.99.

Meta-analysis showed higher blood NEO levels in patients with TB before ATT than after ATT, with moderate effect sizes of 1.13 to 1.46.

Urinary NEO might help diagnosis and disease extent evaluation of PTB.

Pleural NEO can help differentiate TB-induced effusion from malignancy-induced effusion.

Blood NEO might indicate the diagnosis of PTB and its co-infection with HIV and assist in monitoring disease activity during treatment.

Source: https://doi.org/10.1016/j.intimp.2022.109147

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