►► In this large, whole-population, propensity-matched observational study we found no differences in survival to discharge without major morbidity comparing early versus late initiation of PN.
►► We found higher rate of survival in early PN group and also higher rates of major morbidities that are known to be associated with neurodevelopmental impairment.
►► We cannot exclude residual confounding related to survival bias or how sick or unstable a baby was at the time of clinical decision-making about PN initiation.
#nutrition
doi:10.1136/archdischild-2021-322383
