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Supranuclear_gaze_palsy:
Vertical gaze palsy (downgaze affected more) horizontal gaze is intact.
Supranuclear gaze palsy +Parkinson = progressive Supranuclear palsy (PSP)
#Pathogenesis:
Tauopathy : accumulation of tau protiens within the neurons.
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Reference :
Goldman-Cecil medicine 25th ed /QR library
http://static.us.elsevierhealth.com/goldman_cecilmedicine25e_9781455750177/9781455750177_0072