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Testicular_Cancer:
Histologically divided into:A-Germ Cell Tumor (GCT) 95% (#Commonest):
Seminoma GCT(Commones):
Slowly growing malignant tumor of germ cells.
Tumor markers: B HCG in 5%-10%.
AFP: Reference range.
Non seminoma GCT:
More aggressive than Seminoma.
Tumor markers:AFP, HCG.
#subtypes:
1)Choriocarcinoma (rare, most aggressive and Worst prognosis ).
2) Yolk sac carcinoma.
3)Teratoma.
4)Embyronal Carcinoma.
B-Stromal tumor (rare) ~5% :Tumor arises from supportive tissue:
1)Leydig Cell Tumor.
2)Sertolli Cell Tumor.
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Presentation:
1)15-35 yrs old age group.
2)Painless non tender testicular mass.
3) Hydrocele.
4)Dragging sensation.
5)History of Cryptorchidism.
6)Family History.
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Diagnosis_&_Treatment:
Radical inguinal orchidectomy.
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Notes:
Testicular lymphatic drainage: Para aortic LNs.
Scrotal Exploration or transscrotal biobsy in a patient with testicular cancer spread the tumor to the scrotum and subsequently to the inguinal LNs.
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Reference:
1)Medscape.
2)UWORLD
