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#Physiology_Flashback: Hypothalamus produce Gonado-Trophin Re | sᴘᴏᴛ ᴅɪᴀɢɴᴏsɪs

#Physiology_Flashback:

Hypothalamus produce Gonado-Trophin Releasing Hormone ( GnRH) which in turn stimulate the Pituitary gland to release, the Follicular Stimulating Hormone (FSH) & Leutenizing Hormone (LH). FSH & LH influences the gonads (The testis and the ovaries).


#Notes:
FSH stimulate Sertoli cells(S forS) .
LH stimulate Leydig cells(L for L) .
Leydig cells is an endocrine cells that produces Testesteron.
Sertoli cells produces Androgen binding protien to keep Tetstesteron concentration high within the testis.
Leydig cell tumor is the commonest Stromal Tumors.
Stromal tumor present with painless testicular mass and excessive androgen(estrogen and testesteron).
Gynecomastia, acne and precious puberty are the classical symptoms.
It is not an unusual for leydig cell tumor to secrete #Estrogen.
Tetstesteron important in spermatogenesis, male genital organ development and secondary male sex characteristics.


#Reference:
1)Atlas of Histology by Cui
Page 345- 360.
2)UWORLD Surgery.