Three exposures to the COVID spike protein by either infec | UPDATES IN MEDICINE
Three exposures to the COVID spike protein by either infection or vaccination elicit superior neutralizing immunity to all variants of concern
High levels of neutralizing antibodies are successfully elicited against SARS-CoV-2 variants of concern, including omicron, after three exposures to the viral spike protein, mediated by vaccination with BNT162b2 alone or by a combination of vaccination and infection.
Nature Medicine, Published online: 28 January 2022;
