14\ july Q) the criteria related to drug adminstration i | First year Library

14\ july



Q) the criteria related to drug adminstration is ?

A)
* Properties of drug
* Therapeutic objective
* Severity of the disease

Q) What we mean by titration dosage ??

A) Dosage titration mean ;
Continual adjustment of a dose based on patient response

Q) Parenteral administration:
a) Cannot be used with unconsciousness patients
b) Generally results in a less accurate dosage than oral administration
c) Usually produces a more rapid response than oral administration
d) Is too slow for
emergency


A) C

Q) what do we mean by
( First pass metabolism )
Simply ?

A)After a drug is swallowed, it is absorbed by the digestive system and enters the hepatic portal system. It is carried through the portal vein into the liver before it reaches the rest of the body. The liver metabolizes many drugs, sometimes to such an extent that only a small amount of active drug emerges from the liver to the rest of the circulatory system. This first pass through the liver thus greatly reduces the bioavailability of the drug.


Q) Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:
a) Intravenous administration provides a rapid response
b) Intramuscular administration requires a sterile technique
c) Inhalation provides slow access to the general circulation
d) Subcutaneous administration may cause local irritation

A) C , Inhalation provide rapid access to the circulation

Q) Most of drugs are distributed homogeneously
Yes or no ?

A) No , it's affected by many factors that determine the distribution


Q) how we preserve the drugs in the acidc medium of stomach if we want the drug to be absorbed in the intestine ?
A) we applied the Enteric coated preparation
, either to protect the drug from consumed at the stomach level without reach the intestine ( site of action ) , or to protect stomach from the harsh drug ( like aspirin )


Q) Nitroglycerin:
Route of administration ??

- and why not given orally ??

A) Routes :
Iv
Sublingual

- why not orally ? Because it Consumed a lot during first pass metabolism
Aand to be rapidly
absorbed

Q)Usually referred by clinicians :
A ,, proprietary name
B ,, non proprietary name
C ,, chemical name

A) Proprietary

Q) Mention 3 sources for drug an an example for each one ?

A )
-Gentic ( insulin )
-Plant ( nicotine)
- biological ( antibiotics)

Q)Antibactrial:
Is it natural or synthetic ?

A) Natural **