Dermatology

2022-04-22 17:40:28 Open / Comment

2022-04-18 09:44:01 Phytophotodermatitis requires exposure to certain plants or fruits followed by sunlight. Parsnips, parsley, figs, limes, celery, bergamot oranges, and others contain psoralens that react with UVA. Initially there is erythema and blistering followed by streaked hyperpigmentation Open / Comment

2022-04-17 09:42:59 Open / Comment

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2022-04-10 10:07:01 Incontinentia pigmenti is an X_linked dominant genodermatosis which presents in the newborn period with vesicles in a Blaschkoid distribution. A biopsy would show eosinophilic spongiosis with dyskeratotic keratinocytes and pigment incontinence. A gene defect in NEMO has been identified as the cause for the constellation of fingings Open / Comment

2022-04-09 10:06:28 Open / Comment

2022-04-04 11:19:24 Open / Comment

2022-03-30 10:06:01 This patient likely has nephrogenic fibrosing dermopathy (NFD). NFD is an acquired, idiopathic disorder that occurs in renal disease patients. It resembles scleroderma or eosinophilic fasciitis clinically and scleromyxedema histopathologically. Large areas of indurated skin with fibrotic nodules and plaques develop. The extremities are most commonly involved, followed by the trunk. The face, palms and soles are almost never involved. Histopathologically, NFD displays a proliferation of dermal fibroblasts and dendritic cells, thickened collagen bundles, increased elastic fibers, and mucin deposition. Serum protein electrophoresis and immunoelectrophoresis results are negative unlike scleromyxedema, and may be helpful to distinguish the two diseases. NFD is usually a chronic, progressive condition, and favorable responses to medical intervention are anecdotal Open / Comment

2022-03-29 10:05:11 Open / Comment

2022-03-23 08:38:01 Riga-Fede disease is a benign ulcerative granulomatous process that occurs in reaction to chronic, repetitive trauma of the oral mucosa by the teeth. Clinically, it appears as firm, verrucous plaques. It may be associated with an underlying developmental anomaly or underlying neurologic disorder Open / Comment