Elevated neopterin in tuberculosis and co-infection with HIV and the effect of treatment: A systematic review, meta-analysis, and meta-regression
New Paper by USERN Interest Group Meta-analysis showed higher blood NEO levels in patients with active TB than healthy controls, with a large effect size of 1.99.
Meta-analysis showed higher blood NEO levels in patients with TB before ATT than after ATT, with moderate effect sizes of 1.13 to 1.46.
Urinary NEO might help diagnosis and disease extent evaluation of PTB.
Pleural NEO can help differentiate TB-induced effusion from malignancy-induced effusion.
Blood NEO might indicate the diagnosis of PTB and its co-infection with HIV and assist in monitoring disease activity during treatment.
Source: https://doi.org/10.1016/j.intimp.2022.109147
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