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The latest Messages 13
2022-02-23 07:26:01
A 34-year-old man comes to the hospital due to several hours of difficulty swallowing, dry mouth, and blurred vision. The patient has a history of major depression. Examination shows mydriasis and poorly reactive pupils. Electrodiagnostic studies reveal normal nerve conduction velocity but decreased compound muscle action potential (CMAP). Rapid, repetitive nerve stimulation leads to facilitation of CMAP.
276 views04:26
2022-02-22 21:26:01
Educational objective: Chronic thiamine (vitamin 6,) deficiency impairs glucose utilization in the central nervous system. This occurs due to decreased activity of the enzymes that use thiamine as a cofactor (eg, pyruvate dehydrogenase, a-ketoglutarate dehydrogenase, transketolase). Thiamine deficiency can be diagnosed if baseline erythrocyte transketolase activity is low but increases after addition of thiamine pyrophosphate.
368 views18:26
2022-02-22 07:25:08
22 voters119 views04:25
2022-02-22 07:20:07
A 61-year-old man is brought to the emergency department after being found unresponsive on a sidewalk. Paramedics notice that the patient's breath smells of alcohol and that he has vomitus in his mouth. The patient also has agonal respirations, and cardiac monitoring shows pulseless electrical activity. Resuscitation efforts are unsuccessful, and he is pronounced dead on arrival. Autopsy reveals that the cause of death is airway occlusion by aspirated vomitus.
In addition, foci of hemorrhage and necrosis are
seen in the mammillary bodies and gray matter surrounding the third and fourth ventricles.
123 views04:20
2022-02-21 20:23:02
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1.5K views17:23
2022-02-21 20:20:01
50 voters257 views17:20
2022-02-21 20:18:58
An 8-month-old girl is brought to the office for evaluation of irritability and regression of motor skills. Her birth was unremarkable and she appeared to develop normally, but she can no longer sit or roll over. Her parents have also noticed that she startles easily with loud noises. Head circumference measurement is consistent with macrocephaly. Bilateral funduscopic evaluation shows a bright red fovea centralis that is surrounded by a contrasting white macula. Peripheral vision is decreased. Abdominal examination is normal.
280 views17:18
2022-02-21 18:00:28
A 65-year-old woman comes to the office to discuss pain at the posterior chest wall. She was seen 4 months ago for acute shingles involving a right mid-thoracic dermatome. The patient was not treated at that time because she had a delayed presentation and the lesions were already well-crusted and healing. The skin lesions subsequently cleared completely. However, since then, she has had persistent burning and stabbing pain in the same region that has now become severe. She has tried oral acetaminophen without relief. During discussion of treatment options, the patient says she does not want any systemic medications due to concerns about possible side effects. She is started on topical capsaicin cream, and her pain improves markedly over the next several days.
344 views15:00
2022-02-15 21:34:41
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224 views18:34
2022-02-15 19:53:01
74 voters377 views16:53