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Uworld | Step 1

Logo of telegram channel uworldstp1 — Uworld | Step 1 U
Logo of telegram channel uworldstp1 — Uworld | Step 1
Channel address: @uworldstp1
Categories: Education
Language: English
Subscribers: 7.90K
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🌐The Best educational channel for Uworld step 1 that Provides Latest and updated 2021 questions.
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The latest Messages 28

2021-11-19 08:20:06 A 26-year-old man is brought to the emergency department after a high-speed motorcycle collision. The patient was thrown several feet after his motorcycle collided with a car. On arrival, he is profoundly comatose. A CT scan of the head performed within an hour of the event shows no abnormalities. The patient dies several hours later, and autopsy examination is performed. Brain histopathology shows widespread axonal swelling, predominantly at the gray-white junction.
lmmunohistochemical staining of
these axons reveals accumulation of alpha-synuclein and amyloid precursor proteins.
293 views05:20
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2021-11-18 20:25:36
More than the half of the exam is repeated

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113 views17:25
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2021-11-18 20:19:01
In the future, this patient is most likely to suffer from which of the following?
Anonymous Quiz
21%
A. Familial hypercholesterolemia
0%
B. Hypertrophic cardiomyopathy
5%
C.Diabetes mellitus, type 2
2%
D.Peptic ulcer disease
0%
E. Polycystic kidney disease
72%
F. Alzheimer dementia
43 voters164 views17:19
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2021-11-18 20:19:01 A 23-year-old asymptomatic male participates in clinical research and is found to be homozygous for the apolipoprotein E-4 allele.
161 views17:19
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2021-11-18 08:18:01
This patient's condition is best explained by dysfunction of which of the following cellular structures?
Anonymous Quiz
3%
A. Golgi apparatus
3%
B. Lysosomes
8%
C. Mitochondria
74%
D. Peroxisomes
7%
E. Proteasomes
4%
F. Rough endoplasmic reticulum
89 voters314 views05:18
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2021-11-18 08:18:01 A 4-month-old boy is being evaluated for a hereditary metabolic disorder after presenting with failure to thrive and developmental delay. He was born outside the United States and had several seizures during the neonatal period. Physical examination reveals an abnormal head shape with a large anterior fontanelle and widely splayed cranial sutures. Profound hypotonia and hepatomegaly are also noted. Biochemical studies show elevated levels of very long chain fatty acids (VLCFAs) and phytanic acid. Cultured skin fibroblasts show impaired ability to oxidize VLCFAs.
302 views05:18
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2021-11-18 05:04:39
230 views02:04
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2021-11-17 20:17:01
Which of the following is the best next step in management of this patient?
Anonymous Quiz
2%
A.Add atropine
5%
B.Administer pralidoxime
7%
C.Change long-term therapy to edrophonium
83%
D.lncrease pyridostigmine dosage
2%
E. Stop pyridostigmine temporarily
83 voters362 views17:17
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2021-11-17 20:16:02 A 66-year-old man comes to the office with diplopia that progressively worsens toward the end of the day. The patient has no shortness of breath, trouble swallowing, or generalized weakness. He is currently receiving low-dose pyridostigmine for treatment of his condition and claims good compliance without significant side effects. Physical examination reveals fatigable asymmetric ptosis and binocular horizontal diplopia. Infusion of edrophonium elicits a significant improvement in his symptoms.
358 views17:16
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2021-11-17 08:16:01
The patient should be instructed to see his physician immediately if which of the following symptoms occurs?
Anonymous Quiz
7%
A. Abdominal pain
2%
B.Cough
3%
C.Diarrhea
2%
D.Heartburn
74%
E.Skin rash
11%
F. Urine discoloration
90 voters278 views05:16
Open / Comment