UPDATES IN MEDICINE

2022-02-26 20:36:11 ​​​​ More Rapid Spread, Less Severe Disease with Omicron in South Africa

In Gauteng, where the omicron variant was first identified, two thirds of unvaccinated residents were seropositive for SARS-CoV-2, which indicates past infection. Omicron peaked just 1 month after being detected; hospitalizations and deaths did not increase in proportion to cases. Whether this change is related to widespread preexisting immunity or to features of the virus is unclear.

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2022-02-25 18:51:50 Open / Comment

2022-02-23 12:08:30 ​​ Gene Therapy for Sickle Cell Disease

An unprespecified interim analysis of results from a phase 1–2 study of gene therapy for sickle cell disease shows resolution of severe vaso-occlusive events in 25 patients who could be evaluated. In the 24 months before enrollment, these patients had a median of 3.5 severe vaso-occlusive events per year.


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2022-02-20 18:03:03 Get LIVE news coverage on the tense situation between Ukraine and Russia

Ukraine Russia Tensions LIVE

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2022-02-18 10:16:16 ​​ A New Antiviral against Covid-19

Nirmatrelvir plus Ritonavir for Covid-19

Nirmatrelvir is an Mpro inhibitor active against SARS-CoV-2 and is given with ritonavir, a pharmacokinetic enhancer. In this double-blind, placebo-controlled trial, nirmatrelvir plus ritonavir, when given within 5 days after symptom onset to patients at high risk for disease progression, decreased the risk of Covid-19–related hospitalization or death by 87.8%.


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2022-02-16 05:03:37 ​​ Endovascular Therapy for Stroke with Large Infarctions

Endovascular therapy for stroke is generally avoided if the cerebral infarction is large. In a trial conducted in Japan, the percentage of patients who had a good functional outcome at 90 days was higher with endovascular therapy than with medical care, but there were more cerebral hemorrhages with endovascular therapy.


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