UPDATES IN MEDICINE

2022-02-14 17:58:46 ​​ Long-term cardiovascular outcomes of COVID-19

Individuals with COVID-19 are at increased long-term risk for a wide range of cardiovascular disorders, even for individuals who were not hospitalized during the acute phase of the infection.

Nature Medicine,
Published online: 07 February 2022
doi:10.1038/s41591-022-01689-3



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2022-02-13 15:45:40 Get LIVE news coverage on the tense situation between Ukraine and Russia

Ukraine Russia Tensions LIVE

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2022-02-11 18:33:32 ​​ Read the top basic medical science journal CELL JOURNAL

Join and get all the latest articles published on cell journal

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2022-02-10 17:34:37 ​​ Molnupiravir for Early, Outpatient Treatment of Covid-19

Oral outpatient treatment for Covid-19 is needed. In this phase 3, double-blind, randomized, controlled trial, molnupiravir, a small-molecule antiviral, was studied in unvaccinated patients with less than 5 days of Covid-19 illness. By day 29, hospitalization for progression of Covid-19 was lower with molnupiravir (6.8%) than with placebo (9.7%).


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2022-02-08 20:06:29 ​​ Fever of Unknown Origin - NEJM REVIEW

FUO despite a high-quality workup after a reasonable amount of time has elapsed to rule out self-limited fevers remains a challenge. The clinician must pay close attention to the patient history, aided by the development of molecular diagnostic tests, to distinguish infections from other causes.


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2022-02-05 17:34:36 ​​ Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine:
a retrospective, total population cohort study in Sweden


● Interpretation - We found progressively waning vaccine effectiveness against SARS-CoV-2 infection of any severity across all subgroups, but the rate of waning differed according to vaccine type. With respect to severe COVID-19, vaccine effectiveness seemed to be better maintained, although some waning became evident after 4 months. The results strengthen the evidence-based rationale for administration of a third vaccine dose as a booster.


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2022-02-03 14:33:26 ​​ Gene Therapy for β-Thalassemia

Of 23 patients with transfusion-dependent β-thalassemia who received gene-transfected autologous hematopoietic cells, 91% became transfusion independent; the remaining 2 patients had a low level of engraftment of vector-expressing cells. With a median of 29.5 months of follow-up, the average hemoglobin level was 11.7 g per deciliter.


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2022-02-02 20:33:32 ​​​​​​ Deliberate infections give unique Covid insight

The world's first Covid "challenge trial" - which deliberately infected people - gives a unique view on the early stages of the disease.


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