UPDATES IN MEDICINE

2022-02-01 15:40:59 ​​ Guideline for the Evaluation and Diagnosis of Chest Pain
(By AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR )

This clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain in adult patients.


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2022-01-30 10:35:10 ​​ Three exposures to the COVID spike protein by either infection or vaccination elicit superior neutralizing immunity to all variants of concern


High levels of neutralizing antibodies are successfully elicited against SARS-CoV-2 variants of concern, including omicron, after three exposures to the viral spike protein, mediated by vaccination with BNT162b2 alone or by a combination of vaccination and infection.

Nature Medicine, Published online: 28 January 2022;


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2022-01-28 19:36:51 ​​​​ Measles #Review


Measles is a highly contagious, potentially fatal, but vaccine-preventable disease caused by measles virus. Symptoms include fever, maculopapular rash, and at least one of cough, coryza, or conjunctivitis, although vaccinated individuals can have milder or even no symptoms. Laboratory diagnosis relies largely on the detection of specific IgM antibodies in serum, dried blood.......


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2022-01-27 19:22:52 ​​ Similar or different type of vaccine as booster

● Homologous and Heterologous Covid-19 Booster Vaccinations

Participants who had been fully vaccinated with current Covid-19 vaccines received homologous or heterologous boosters, and their immune response was measured on days 15 and 29. Homologous boosters increased neutralizing antibody titers by a factor of 4 to 20, whereas heterologous boosters increased titers by a factor of 6 to 73.


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2022-01-25 18:59:05 ​​ Clinical severity of the omicron variant in South Africa

● Interpretation - Our early analyses suggest a significantly reduced odds of hospitalisation among individuals with omicron versus non-omicron infections diagnosed during the same time period. omicron-infected individuals had a significantly reduced odds of severe disease compared with individuals infected earlier with the delta variant. Some of this reduced severity is probably a result of previous immunity.


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