Uworld | Step 1

2022-06-21 08:02:01 Electric stimulation of the musculocutaneous nerve causes a rapid twitch of the biceps muscle. Electron microscopy shows numerous vesicles within the musculocutaneous nerve terminals. Open / Comment

2022-06-20 21:01:01 Educational objective: Pudenda! nerve injury can occur due to excessive stress on the pelvic floor during labor and delivery (eg, prolonged second stage). Nerve injury leads to denervation and weakness of the perinea! musculature (eg, external anal sphincter), which can present as new-onset fecal incontinence. Open / Comment

2022-06-17 08:56:02 A 23-year-old woman is brought to the emergency department unconscious after a motor vehicle accident. The patient was texting on her cell phone and was not wearing a seatbelt during the incident. She has no known medical problems and takes no medications. Her temperature is 36. 7 C (98 F), blood pressure is 155/90 mm Hg, pulse is 62/min, and respirations are 1 O/min. A linear skull fracture at the junction of the frontal, parietal, temporal, and sphenoid bones is seen on head CT scan. Open / Comment

2022-06-16 08:55:10 A 31-year-old female with new-onset generalized tonic-clonic seizures has an intracranial mass detected on head CT scan. Biopsy of the mass reveals neoplastic cells that stain positive for synaptophysin and negative for glial fibrillary acidic protein. Open / Comment

2022-06-15 19:55:13 Educational objective: Botulinum toxin blocks the presynaptic exocytosis of ACh vesicles, causing impaired muscarinic and nicotinic neurotransmission; it characteristically presents as a symmetric, descending paralysis that first manifests with cranial nerve abnormalities, often following consumption of home-canned foods. Open / Comment

2022-06-15 08:54:02 Open / Comment

2022-06-06 08:43:01 Open / Comment

2022-06-06 08:43:01 A 62-year-old woman comes to the office due to tingling and numbness in her feet over the last several months. The patient has also noticed a small ulcer on her right foot that "doesn't seem to be healing." Medical history is significant for long-term diabetes, hypertension, and gout. Physical examination shows decreased pain sensation over both feet and bilateral absence of ankle reflexes. Open / Comment

2022-06-06 02:54:58 https://t.me/studentdoctor Open / Comment

2022-06-05 20:43:01 Educational objective: Delayed cerebral ischemia due to cerebral vasospasm usually presents 3-12 days after the initial subarachnoid hemorrhage (SAH) with an acute change in mental status and/or new focal neurological deficits. Nimodipine, a selective calcium channel blocker, improves outcomes in patients with cerebral vasospasm by inducing cerebral vasodilation and decreasing calcium-dependent excitotoxicity. Open / Comment