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The latest Messages 4
2022-06-05 08:42:01
35 voters131 views05:42
2022-06-05 08:41:01
132 views05:41
2022-06-04 20:40:24
Educational objective: Creutzfeldt-Jakob disease is a prion disease characterized by rapidly progressive dementia, myoclonus, and death within a year of symptom onset.
It is caused by the accumulation of an abnormally folded (ie,
beta pleated sheet) protein that is resistant to proteases and can trigger similar conformational changes in other normally folded proteins.
279 views17:40
2022-06-04 08:40:19
95 voters391 views05:40
2022-06-04 08:38:01
A 57-year-old man is hospitalized for aspiration pneumonia. The patient was healthy and worked as an engineer without difficulty until about 4 months ago. Since that time, he has developed severe confusion, mood changes, and memory impairment and had to take medical leave from work. The patient is now completely dependent on his wife for toileting, feeding, and general self-care. Physical examination shows disorientation and sporadic, jerky extremity movements. During hospitalization, the patient lapses into a coma and dies. Postmortem examination of his brain shows widespread atrophy of the cerebral cortex and cerebellum.
367 views05:38
2022-06-03 21:38:01
Educational objective: Schwannomas present histologically with a biphasic pattern of cellularity (Antoni A and B areas) and S-100 positivity (indicating neural crest origin). Schwannomas can arise from the peripheral nerves, nerve roots, and cranial nerves (except CN II and CN I). Acoustic neuromas are the most common type of intracranial schwannoma and are located at the cerebellopontine angle at CN VIII.
416 views18:38
2022-06-03 08:38:01
125 voters484 views05:38
2022-06-03 08:37:01
An intracranial mass is removed from a 33-year-old patient. The mass is composed of cells that have elongated, wavy nuclei. A biphasic pattern of growth is identified, consisting of areas of dense cellularity interspersed with less dense myxoid regions. The cells show diffuse S-100 immunoreactivity.
463 views05:37
2022-06-02 20:37:01
Educational objective: Lesions of the jugular foramen can result in jugular foramen (Vernet) syndrome, which is characterized by the dysfunction of cranial nerves IX, X, and XI. Symptoms include dysphagia, hoarseness, loss of gag reflex on the ipsilateral side, and deviation of the uvula toward the normal side.
84 views17:37
2022-06-02 08:37:01
70 voters282 views05:37