Steroidify

2021-04-24 00:08:13 ​​ Health Pro Tip: self diagnosing sleep apnea.

One of the biggest problems for bodybuilders (especially when they are heavy category) is sleep apnea, the airways can be obstructed for many reasons (including the neck muscles) and this can end up causing sleep apnea, today im going to explain a little trick to self-diagnose it (it is not 100% accurate and you will always require the help of a professional to verify it).


Method

We are going to use the Mallampati score, in the photo we can see four similar but different images, the higher the score, the more risk we will have of suffering from sleep apnea.

You will need another person to help you out.

You should be sitting upright with your head in a neutral position, after that you will need to extend your tongue and your partner will need to take a look at your overall mouth structure and compare it with the picture.


Score

A score of III or IV would mean that you have a higher risk of your tissue making it difficult for you to breathe causing sleep apnea, if you feel tired or snore often you should see the doctor.


#Protip #Health #Sleepapnea Open / Comment

2021-04-23 01:55:00 ​​ Bloodwork tip: measuring E2

There are different methods to measure Estradiol levels, most of them were designed for women and in men they tend to give completely wrong results, today I am going to mention which methods will give wrong results and which ones will not.


Unsuitable methods.

Radioimmunoassay Chemiluminescence Immunoenzymatic assay Immunoradiometric

All of these methods would give erroneous or very inaccurate results.


Correct method

Ultrasensitive estradiol, measured by LC-MS / MS method.

This method would give a completely correct estradiol measurement.

#Tip #Bloodwork #E2 #Estradiol Open / Comment

2021-04-22 22:41:46 Product of the week #2 winners:
PHARMASUST 300 / Pharmacom Labs
OXANDROLONOS / Pharmacom Labs
ARIMIMED 1 / Deus Medical
50% discount is ON for the next 48 hours!
Cheers! Open / Comment

2021-04-20 21:49:35 Steroidify pinned «​​ We are pleased to announce that our contest is going to the voting phase which will determine the finalists to fight for the 1st prize - $1000! Vote for the best arm physique by clicking VOTE FOR THE PARTICIPANTS here ... @tournament_master_bot…» Open / Comment

2021-04-20 01:56:13 ​​ Did you know that: liver damage can induce gyno.


Most of the population thinks that gynecomastia can only be caused by steroids, either due to a high presence of estrogens or an elevation in prolactin due to the use of Nandrolone or Trenbolone (completely false myth), gynecomastia can also be due to a malfunction of the liver.


Explanation

The liver metabolizes and conjugates more than 50% of estrogens , and it is done mainly by two phases (Phase 1 and Phase two pathways).

When the liver is damaged the metabolism of estrogens is altered, both within the liver and in the extra hepatic tissues, causing an elevation of the level of estrogens and therefore causing gynecomastia .


Solutions

Take care of your liver while taking orals .
Stop drinking like MFs.


#Didyouknow #Liver #Gyno Open / Comment

2021-04-15 21:20:17 ​​ Training Pro Tip: occlusion training

Occlusion training or kaatsu has increased in popularity because it is a very simple way to increase the intensity of the training, in today's post we are going to learn what it consists of.


What is kaatsu?

It is a training method created in Japan that bases its effectiveness on the different responses at the anabolic level through ischemic conditions.

A small tourniquet is applied on the limb to be trained, restricting the blood flow to that area and causing a very interesting anabolic stimulus.


Advantages

Greater recruitment of fast fibers .

It generates a great local fatigue, it can be useful for a short but intense training .

It has a cross-limb effect , both limbs benefit from the kaatsu effect.

Increases ROS levels.


Disadvantages

It creates a great stimulus and fatigue, there have been cases of rhabdomyolysis in workouts that have not been correctly planned.

If the tourniquet is tightened too hard or held for a long time, it can cause pulmonary embolisms or thrombosis, I recommend not using it for more than 10 minutes .

In the next article on kaatsu I will give more guidelines.

#Protip #Training #Kaatsu Open / Comment

2021-04-14 22:46:33 ​​ We are pleased to announce that our contest is going to the voting phase which will determine the finalists to fight for the 1st prize - $1000!

Vote for the best arm physique by clicking VOTE FOR THE PARTICIPANTS here ... @tournament_master_bot

You have 3 votes (multiple voting is possible) and 2 weeks to help your brothers to win the title!

See you in the finals! Open / Comment

2021-04-14 00:51:45 ​​ Protip: Genetics and Fatloss

Genetics greatly influences fat loss, depending on your genes there will be a specific type of diet that is better.


FABP2 (rs1799883)

FABP2 refers to the intestinal fatty acid binding protein 2, which is a protein located in the cytosol of the intestinal epithelium and is associated with the metabolism of long chain fatty acids.

At rs1799883 a transition occurs at codon 54 resulting in a replacement of Alanine (Ala) with Threonine (Tr), the wild-type allele pattern for FABP2 is Ala / Ala while the mutant is Ala / Tr or Tr / Tr.

People with the mutant-type allele pattern would take advantage of a low-carb, high-fat diet while people with the wild-type allele pattern would take more advantage of a high-carb , low-fat diet.


PPARG2 (rs1801282)

This is the peroxisome proliferator activated receptor gamma-2 gene, which is an isoform of the PPARG gene. PPARG2 is found mainly in adipocytes and has a very important role in adipocyte differentiation.

At codon 12 of exon B in rs18001282 a mutation occurs consisting of a transition from alanine (Ala) to proline (Pro). The wild type allele pattern of PPARG2 is Pro / Pro, while the mutant type is Pro / Ala or Ala / Ala.

People with the mutant-type allele pattern would benefit more from a low-fat, high-carbohydrate diet.


ADRB3 (rs4994)

This is the beta-3 adrenergic receptor gene, which is found mainly in adipocytes and its function is related to lipid metabolism and thermogenesis.

At codon 64, a mutation can occur consisting of a transition from tryptophan (Trp) to arginine (Arg). The wild type allele pattern is Trp / Trp while the mutant type is Arg / Arg or Trp / Arg.

People with the mutant-type allele pattern would benefit more from a moderate carbohydrate and fat diet, those with a wild-type allele pattern would take advantage of a very high intake of PUFAs .


ADRB2 (rs1042713 and rs1041714)

This is the beta-2 adrenergic receptor gene which is distributed throughout the body, with a large presence in adipocytes and plays a very important role in lipid metabolism and thermogenesis.

The two most common genetic mutations in this gene occur at codons 16 and 27, respectively.

At codon 16 (rs1042713) arginine (Arg) replaces glycine (Gly); the homozygous allele pattern for Glycine is that of the wild type (Gly / Gly) while the other two are of the mutant type.
At codon 27 (rs1041714) glutamic acid (Glu) replaces glutamine (Gln); the homozygous allele pattern for Glutamine is of the wild type (Gln / Gln) while the other two are of the mutant type.

People with a wild-type allele pattern at codon 16 would need a greater caloric deficit to achieve the same weight loss , the same would happen for those with a mutant-type allele pattern at codon 27 .

#Genetics #Fatloss #Protip Open / Comment

2021-04-09 21:18:44 ​​ MythBusters: Nandrolone and Trenbolone elevates prolactin.

Normally the gym bros believe that Trenbolone and Nandrolone raise prolactin, that is why it is usually advisable to take Cabergoline or B6 during the cycle ... but this is completely false, if you have elevated prolactin it will be due to other causes such as damage to the hypophysis, in the thyroid glands or due to the abuse of HGH.


Explanation and scientific evidence

To date, there is not a single clinical trial in humans or cattle (both steroids are often used a lot in cows, and their mammary tissues are very easy to analyze) that demonstrate that the use of Tren or Nandrolone causes an increase in the prolactin.

In bovine animals : no change was observed in their prolactin levels .

In humans : it was seen that the use of Nandrolone decreased by almost HALF the prolactin levels (71ng / mL to 42ng / mL) that were in the base and testosterone instead increased the prolactin levels (71ng / mL to 78ng / mL ).

The main culprit for the increases in prolactin levels during steroid cycles are estrogens and aromatizable steroids , since local aromatization increases prolactin levels according to clinical trials and, as seen in transgender women, elevated estrogen levels increase prolactin .

#Mythbusters #Prolactin #Tren #Decadick Open / Comment